on edge
Synonym discussion
Sense: idiom/1
All four words describe a state of mental or physical discomfort, but they differ in intensity and focus. 'Tense' emphasises the physical symptoms — tight muscles, clenched jaw, shallow breathing — and is the closest match for 'on edge' in sense 1. 'Jumpy' is more informal and suggests a heightened startle response, as if every sudden noise makes you flinch. 'Uneasy' is milder: a vague sense that something is wrong, without the sharp agitation of 'on edge'. 'Anxious' overlaps strongly with sense 2 and adds a component of worry about the future. For example, you might feel 'tense' before giving a speech, 'jumpy' alone in a dark house, 'uneasy' about a decision you just made, and 'anxious' about an upcoming doctor's appointment.
Etymology
The phrase 'on edge' dates from the early 1800s and draws on the image of standing on the edge of a blade or a cliff — a precarious, unstable position where any small movement could lead to disaster. Over time, this physical sense of being poised at a dangerous boundary came to describe a person's mental state of tension and nervous expectation.