serpin
serpin — noun
1. A serpin is a type of protein that belongs to a family of similar molecules foun
A serpin is a type of protein that belongs to a family of similar molecules found in living organisms. Most serpins work by blocking enzymes called proteases that normally break down other proteins. Some well-known serpins include antithrombin, which helps control blood clotting, and antitrypsin, which protects lung tissue. However, some members of this family — such as ovalbumin (a protein in egg whites) and angiotensinogen (involved in blood pressure regulation) — no longer perform this blocking function.
Dr. Yara Okafor’s team identified a serpin that reduces gut inflammation by blocking a specific protease.
serpin that + [effect] by blocking + [enzyme]
A serpin called antithrombin is made in the liver to stop blood clots from growing too large.
serpin called + [name], made in + [organ]
Doctors often check a patient’s serpin levels when they suspect a lung disorder such as emphysema.
Ravindra’s genetic test showed a serpin mutation that causes the protein to fold incorrectly.
The Watanabe lab is testing a drug that helps liver cells produce correctly folded serpin proteins.
- protease inhibitor
a broader category; serpins are one specific family of protease inhibitors with a characteristic structure and mechanism
文法句型
serpin + called/named + [example]
用法筆記
Frequently appears in the plural form serpins when referring to the family as a whole. The singular is used for a specific member (e.g., antithrombin is a serpin).