fluoxetine
Synonym discussion
Sense: noun/1
These four terms sit at different layers of specificity. 'Antidepressant' is the broadest umbrella — any medicine used to treat depression, including older classes like tricyclics. 'SSRI' (selective serotonin reuptake inhibitor) names a sub-class that works by raising serotonin levels in the brain; fluoxetine is one member, but so are sertraline and citalopram. 'Fluoxetine' is the specific chemical compound used in research papers, prescriptions, and pharmacy labels. 'Prozac' is the original brand name and the term most patients recognise in daily conversation. In a magazine article you might write 'a doctor prescribed Prozac', but in a medical chart the same medication appears as 'fluoxetine 20 mg'.
Common collocations
Nouns
- fluoxetine treatment
- fluoxetine dose
- fluoxetine tablet
Phrases
- start someone on fluoxetine
- respond to fluoxetine
- switch from fluoxetine
Prepositions
- on fluoxetine
- with fluoxetine
Etymology
Coined in the 1970s by chemists at Eli Lilly who developed the compound. The name combines 'fluoro-' (signaling the three fluorine atoms in its structure, from Latin 'fluere' meaning to flow) with '-xetine', an ending shared by several SSRIs such as paroxetine. The drug was first approved for use in the United States in 1987 under the brand name Prozac.