inoperable
Word family
Synonym discussion
Sense: adjective/1
All four words describe a medical condition that cannot be fixed, but they differ in scope and context. 'Inoperable' is the narrowest — it refers specifically to conditions where surgery cannot help, though other treatments (chemotherapy, radiation) may still be possible. 'Untreatable' is broader: no effective treatment of any kind exists. 'Incurable' is broader still: the condition cannot be permanently eliminated, though symptoms can often be managed. 'Non-resectable' is a surgeon's technical term meaning a tumour cannot be cut out; it overlaps with 'inoperable' but is rarely used outside operating rooms. For example, a lung tumour might be 'inoperable' (too risky to cut out) but still 'treatable' with radiation. A late-stage cancer might be both 'inoperable' and 'incurable,' yet remain 'treatable' with palliative care.
Common collocations
Etymology
The word 'inoperable' was formed by adding the prefix 'in-' (meaning 'not') to 'operable', which comes from the Latin verb 'operari' (to work) via the suffix '-abilis' (able). Its earliest uses in English, dating from the mid-1800s, were medical — describing tumours that could not be removed by surgery. The broader sense ('a machine or system that cannot work') developed in the early 1900s as technology expanded.
First known use
1886
1886, in the meaning defined at sense 1