serpin
serpin — 名詞
1. A serpin is a type of protein that belongs to a family of similar molecules foun
絲胺酸抑制劑
一類抑制蛋白酵素的蛋白質分子家族
A serpin is a type of protein that belongs to a family of similar molecules found in living organisms. Most serpins work by blocking enzymes called proteases that normally break down other proteins. Some well-known serpins include antithrombin, which helps control blood clotting, and antitrypsin, which protects lung tissue. However, some members of this family — such as ovalbumin (a protein in egg whites) and angiotensinogen (involved in blood pressure regulation) — no longer perform this blocking function.
Dr. Yara Okafor’s team identified a serpin that reduces gut inflammation by blocking a specific protease.
Yara Okafor 博士的研究團隊發現一種絲胺酸抑制劑，可通過抑制特定蛋白酵來減輕肠道發炎。
serpin that + [effect] by blocking + [enzyme]
A serpin called antithrombin is made in the liver to stop blood clots from growing too large.
一種名為抗凝血酮的絲胺酸抑制劑由肝臟製造，可防止血栓長得過大。
serpin called + [name], made in + [organ]
Doctors often check a patient’s serpin levels when they suspect a lung disorder such as emphysema.
醫生經常在懷疑患者有肺氣腫等肺部疾病時，檢查其絲胺酸抑制劑濃度。
Ravindra’s genetic test showed a serpin mutation that causes the protein to fold incorrectly.
Ravindra 的基因檢測顯示一種絲胺酸抑制劑突變，導致蛋白質折疊錯誤。
The Watanabe lab is testing a drug that helps liver cells produce correctly folded serpin proteins.
Watanabe 實驗室正在測試一種藥物，協助肝臟細胞製造正確折疊的絲胺酸抑制劑蛋白質。
- protease inhibitor
a broader category; serpins are one specific family of protease inhibitors with a characteristic structure and mechanism
文法句型
serpin + called/named + [example]
用法筆記
Frequently appears in the plural form serpins when referring to the family as a whole. The singular is used for a specific member (e.g., antithrombin is a serpin).