non-responder
/ˌnɒn.rɪˈspɒn.dər/ (bre, ipa) · /ˌnɑːn.rɪˈspɑːn.dɚ/ (ame, ipa)
non-responder — 名詞
1. a sick person whose condition does not get better after being given a particular
無效病患
對某種藥物或療法毫無反應的患者
a sick person whose condition does not get better after being given a particular medical treatment, such as a drug or therapy.
About one in five chemotherapy patients turn out to be non-responders, so Dr. Hamza tried a different drug on Felipe.
大約每五位化療病患中就有一位屬於無效病患，因此 Hamza 醫師讓 Felipe 改用另一款藥物。
noun phrase: turn out to be non-responders
Researchers at the Taipei clinic are studying why some asthma patients become non-responders to inhaled steroids.
台北一間診所的研究人員正在探討為何部分氣喘病患會變成吸入型類固醇的無效病患。
collocation: non-responders to [treatment]
Lakshmi was classed as a non-responder after three months of antidepressants brought no change in her mood.
Lakshmi 服用抗憂鬱藥物三個月卻完全沒有改善心情，因此被歸類為無效病患。
Doctors switched Obi's medication once the lab tests confirmed he was a non-responder to the first antibiotic.
實驗報告確認 Obi 對第一線抗生素是無效病患後，醫師便為他更換藥物。
The hospital keeps a register of non-responders so future trials can recruit them as a separate group.
醫院建立一份無效病患名冊，方便未來的臨床試驗將他們納入獨立組別招募。
- treatment-resistant patient
longer descriptive phrase; emphasises that the body is actively resisting
- refractory patient
more technical medical register; common in oncology and psychiatry
- responder
patient whose condition improves with the treatment
文法句型
a non-responder to [treatment]
用法筆記
Frequently appears in clinical trial reports and medical journals; the noun is typically paired with the preposition 'to' plus a treatment, drug, or therapy name.
常見錯誤
2. someone who has been asked for information, usually in a survey or questionnaire
未回覆者
對問卷或調查未做出回應的人
someone who has been asked for information, usually in a survey or questionnaire, but does not reply.
Out of 800 households in Christopher's survey, roughly 200 turned out to be non-responders.
Christopher 調查的 800 戶人家中，大約有 200 戶屬於未回覆者。
collocation: turned out to be non-responders
Ada sent reminder emails to every non-responder on the customer-feedback list.
Ada 對顧客回饋名單上的每一位未回覆者都寄出提醒信。
noun phrase as object: reminder emails to every non-responder
To reduce bias, the research team phoned a sample of non-responders and asked them the same questions.
為了降低偏差，研究團隊抽選一部分未回覆者並以電話詢問相同的問題。
Jessica noted that older participants were less likely to be non-responders than people in their twenties.
Jessica 注意到年長受訪者成為未回覆者的比例低於二十多歲的人。
Xiu's report compared the income levels of non-responders with those of the people who returned the form.
Xiu 的報告比較了未回覆者與已交回表格者的所得水準。
- non-respondent
preferred term in formal statistics and survey methodology textbooks
- non-participant
broader; covers people who never agreed to take part, not just those who failed to reply
- respondent
person who answers the survey
文法句型
a non-responder to [survey / message]
用法筆記
Distinguish from sense 1 (medical context): this sense applies to survey, polling, and questionnaire methodology. The 'request for information' here is a written or spoken question, not a medical treatment.